Fast and effective

Apoquel is the #1 prescribed oral medicine for allergic itch1 and is effective for2,3:

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Flea allergy

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Food allergy

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Atopic dermatitis

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Contact allergy

Both Apoquel Chewable and Apoquel Tablet provide rapid relief of allergic itch within 24 hours2,3

Apoquel Chewable tablet is expected to have comparable efficacy to Apoquel Tablet after the first dose, and comparable safety to Apoquel Tablet.

Apoquel Chewable is safe and effective when used according to the labeling.

Apoquel Tablet began to control allergic itch within 4 hours

Apoquel Tablet delivered fast relief that began to control itch within 4 hours, comparable to oral steroids, in dogs with allergic dermatitis4,5

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*The dose of prednisolone was lowered at Day 6 to account for the real-world dosing scenario of prednisolone.

Apoquel Tablet provided significant reduction in skin inflammation due to allergic dermatitis

Apoquel Tablet leads to significant reduction in skin inflammation over the long term6,7:

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Controls inflammation due to allergic dermatitis and atopic dermatitis3-8

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Controls pruritus due to allergic dermatitis and atopic dermatitis3-8

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Reduces clinical signs of inflammation due to allergic dermatitis comparable to steroids4,5

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Controls inflammation due to allergic dermatitis and atopic dermatitis3-8

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Controls pruritus due to allergic dermatitis and atopic dermatitis3-8

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Reduces clinical signs of inflammation due to allergic dermatitis comparable to steroids4,5

Apoquel Tablet was shown to be as effective as steroids in reducing skin inflammation due to allergic dermatitis at all time points4,5

Real-world results8

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BEFORE APOQUEL TABLET

BEFORE APOQUEL TABLET

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AFTER 48 HOURS OF APOQUEL TABLET

AFTER 48 HOURS OF APOQUEL TABLET

Marley

Boston Terrier Mix

Age: 5 years

30 lb

Additional Studies and Results

Apoquel Tablet controlled allergic itch within 24 hours3

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Apoquel Tablet provided significant long-term itch relief 6,7

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Apoquel Tablet exhibited faster onset of relief than Atopica® (cyclosporine capsules, USP) in the control of pruritus in dogs with atopic dermatitis8,10

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References: 1. Data on file, Monthly Kynetec Report, September 2022, Zoetis Inc. 2. Data on file, Study Report A161C-US-21-C02, 2022, Zoetis Inc. 3. Cosgrove SB, Wren JA, Cleaver DM, et al. Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis. Vet Dermatol. 2013;24(5):479-e114. doi:10.1111/vde.12047 4. Gadeyne C, Little P, King VL, et al. Efficacy of oclacitinib (Apoquel®) compared with prednisolone for the control of pruritus and clinical signs associated with allergic dermatitis in client-owned dogs in Australia. Vet Dermatol. 2014;25(6):512-e86. doi:10.1111/vde.12166 5. Data on file, Study No. A161R-AU-12-096, Zoetis Inc. 6. Cosgrove SB, Wren JA, Cleaver DM, et al. A blinded, randomized, placebo-controlled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (Apoquel®) in client-owned dogs with atopic dermatitis. Vet Dermatol. 2013;24(6):587-e142. doi:10.1111/vde.12088 7. Data on file, Study No. 1962C-60-10-A16, Zoetis Inc. 8. Little PR, King VL, Davis KR, et al. A blinded, randomized clinical trial comparing the efficacy and safety of oclacitinib and ciclosporin for the control of atopic dermatitis in client-owned dogs. Vet Dermatol. 2015;26(1):23-e8. doi:10.1111/vde.12186 9. Data on file, Pet Owner Case Study-Marley, 2015, Zoetis Inc. 10. Data on file, Study No. 6962R-14-10-025, 2013, Zoetis Inc.

Cytopoint Indications

Cytopoint has been shown to be effective for the treatment of dogs against allergic dermatitis and atopic dermatitis.

Apoquel and Apoquel Chewable Indications

Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.

Apoquel and Apoquel Chewable Important Safety Information

Do not use Apoquel or Apoquel Chewable in dogs less than 12 months of age or those with serious infections. Apoquel and Apoquel Chewable may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Apoquel and Apoquel Chewable have not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. Apoquel and Apoquel Chewable have been used safely with many common medications including parasiticides, antibiotics and vaccines.

See full Prescribing Information for Apoquel and full Prescribing Information for Apoquel Chewable.

Cytopoint Indications

Cytopoint has been shown to be effective for the treatment of dogs against allergic dermatitis and atopic dermatitis.

Apoquel and Apoquel Chewable Indications

Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.

Apoquel and Apoquel Chewable Important Safety Information

Do not use Apoquel or Apoquel Chewable in dogs less than 12 months of age or those with serious infections. Apoquel and Apoquel Chewable may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Apoquel and Apoquel Chewable have not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. Apoquel and Apoquel Chewable have been used safely with many common medications including parasiticides, antibiotics and vaccines.

See full Prescribing Information for Apoquel and full Prescribing Information for Apoquel Chewable.