Apoquel® (oclacitinib tablet) Dosing & Administration
How to dose Apoquel
0.4-0.6 mg/kg
(0.18-0.27 mg/lb)
Twice daily (BID) for up to 14 days
Continue therapy once daily (SID) thereafter for maintenance
May be given with or without food
May discontinue without tapering
Apoquel Dosing Guide
Apoquel Tablets



3.6 mg



5.4 mg



16 mg
Quartering tablets is extra-label use. Apoquel tablets are scored to be halved to ensure that the ingredients are equally distributed. We cannot be sure of accurate dosing when tablets are quartered, and thus this practice is not recommended.
Apoquel Dosing Guide
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Apoquel Indications
Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.
Apoquel Important Safety Information
Do not use Apoquel in dogs less than 12 months of age or those with serious infections. Apoquel may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Apoquel has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. Apoquel has been used safely with many common medications including parasiticides, antibiotics and vaccines.
For more information, please see the full Prescribing Information.